MC31335 甘氨鹅脱氧胆酸钠盐 [16564-43-5]
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详情
| 英文名称 | Sodium glycochenodeoxycholate |
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| 别名 | 甘氨鹅去氧胆酸钠; 甘氨鹅脱氧胆酸钠;;N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt; Sodium glycochenodeoxycholate; 3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt; |
| 分子式 | C26H42NNaO5 |
| CAS号 | 16564-43-5 |
| 分子量 | 471.61 |
| MDL | MFCD00036743 |
| 名称 | 甘氨鹅脱氧胆酸钠盐 |
| 介绍 | 97% |
文档信息
| 文档 | COA NMR HPLC MSDS Datasheet |
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生物活性
| 描述 | Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) 可诱导肝细胞凋亡。 |
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| 相关类别 |
研究领域 >> 癌症 信号通路 >>细胞凋亡>>细胞凋亡 |
| 参考文献 |
[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27. |
物理化学性质
| 沸点 | 655.6ºC at 760mmHg |
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| 分子式 | C26H42NNaO5 |
| 分子量 | 471.605 |
| 闪点 | 350.3ºC |
| 精确质量 | 471.296082 |
| PSA | 109.69000 |
| LogP | 2.65030 |
| 外观性状 | 5.74E-20mmHg at 25°C |
| 蒸汽压 | 避光，阴凉干燥处，密封保存 |
英文别名
| 别名 |
Sodium glycochenodeoxycholate 3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt Sodium {[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino}acetate Glycine, N-((3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl)-, monosodium salt N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt Glycine, N-[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) Glycochenodeoxycholic acid sodium salt |
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