MC50892 螺旋霉素 [8025-81-8]
详情
| 英文名称 | Spiramycin |
|---|---|
| 别名 | NA |
| 分子式 | C43H74N2O14 |
| CAS号 | 8025-81-8 |
| 分子量 | 843.06 |
| MDL | MFCD01314545 |
| 名称 | 螺旋霉素 |
| 介绍 | >90.0%(HPLC) |
文档信息
| 文档 | COA NMR HPLC MSDS Datasheet |
|---|
生物活性
| 描述 | Pilocarpine Hydrochloride 是一种选择性的 M3 型毒蕈碱乙酰胆碱受体 (M3 muscarinic receptor) 激动剂。 |
|---|---|
| 相关类别 |
研究领域 >> 感染 信号通路 >> 抗感染 >>细菌 |
| 靶点 | Bacterial[1] |
| 参考文献 |
[1]. Nguyen HC, et al. Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens. Antimicrob Agents Chemother. 2013 Aug;57(8):3836-42. |
物理化学性质
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 913.7±65.0 °C at 760 mmHg |
| 分子式 | C43H74N2O14 |
| 分子量 | 843.053 |
| 闪点 | 506.4±34.3 °C |
| 精确质量 | 842.513977 |
| LogP | 3.06 |
| 蒸汽压 | 0.0±0.6 mmHg at 25°C |
| 折射率 | 1.550 |
英文别名
| 别名 |
[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name) Leucomycin Foromacidin Provamycin [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde Spiramycin I Rovamycin |
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