MCA25762 牛血清白蛋白 低内毒素 干细胞级 [9048-46-8]
详情
英文名称 | Albumin(bovine serum) |
---|---|
别名 |
牛白蛋白 |
纯度 | 98% |
CAS号 | 9048-46-8 |
MDL | MFCD00130384 |
form | lyophilized powder |
mol wt | ~66 kDa |
storage temp. | 2-8°C |
纯化方式 | 色谱层析法 |
特点 |
高细胞滴度 |
Bioburden |
100 cfu/g |
内毒素 | 1 EU/mg |
Moisture | 5% |
Mycoplasma | None Detected |
pH (4% aq soln) | 6.5 - 7.5 |
Virus | None Detected |
Solubility (20%) |
Dissolves completely in 20 min at 20-25°C |
Protein | Albumin |
Gene | ALB |
Organism | Bos taurus (Bovine) |
Function |
Binds water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (PubMed:22677715). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (Probable). The rank order of affinity is zinc > calcium > magnesium (Probable). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017). Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017). |
Caution |
A peptide arising from positions 165 to 173 was originally termed neurotensin-related peptide (NRP) and was thought to regulate fat digestion, lipid absorption, and blood flow. |
Subcellular location | Extracellular region or secreted |
Allergenic properties | Can cause allergic reactions in humans |
Tissue specificity | Plasma |
Sequence |
10 20 30 40 50 |