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MCA25762 牛血清白蛋白 低内毒素 干细胞级 [9048-46-8]

Bovine Serum Albumin in complex with Ketoprofen
Bovine Serum Albumin in complex with Ketoprofen bovine serum albumin [Bos taurus]-gene

详情

英文名称 Albumin(bovine serum)
别名

牛白蛋白
蛋白粉
BSA
Albumin bovine serum
Bovine albumin
BSA
Bovine Serum Albumin

纯度 98%
CAS号 9048-46-8
MDL MFCD00130384
form lyophilized powder
mol wt ~66 kDa
storage temp. 2-8°C
纯化方式 色谱层析法
特点

高细胞滴度
高一致性
无变性蛋白

Bioburden

100 cfu/g

内毒素 1 EU/mg
Moisture 5%
Mycoplasma None Detected
pH (4% aq soln) 6.5 - 7.5
Virus None Detected
Solubility (20%)

Dissolves completely in 20 min at 20-25°C

Protein Albumin
Gene ALB
Organism Bos taurus (Bovine)
Function

Binds water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).

Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (Probable). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (PubMed:22677715).

The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (Probable). The rank order of affinity is zinc > calcium > magnesium (Probable). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (PubMed:6234017).

Does not prevent iron uptake by the bacterial siderophore aerobactin (PubMed:6234017).

Caution

A peptide arising from positions 165 to 173 was originally termed neurotensin-related peptide (NRP) and was thought to regulate fat digestion, lipid absorption, and blood flow.

Subcellular location Extracellular region or secreted
Allergenic properties Can cause allergic reactions in humans
Tissue specificity Plasma
Sequence
        10         20         30         40         50
MKWVTFISLL LLFSSAYSRG VFRRDTHKSE IAHRFKDLGE EHFKGLVLIA
60 70 80 90 100
FSQYLQQCPF DEHVKLVNEL TEFAKTCVAD ESHAGCEKSL HTLFGDELCK
110 120 130 140 150
VASLRETYGD MADCCEKQEP ERNECFLSHK DDSPDLPKLK PDPNTLCDEF
160 170 180 190 200
KADEKKFWGK YLYEIARRHP YFYAPELLYY ANKYNGVFQE CCQAEDKGAC
210 220 230 240 250
LLPKIETMRE KVLASSARQR LRCASIQKFG ERALKAWSVA RLSQKFPKAE
260 270 280 290 300
FVEVTKLVTD LTKVHKECCH GDLLECADDR ADLAKYICDN QDTISSKLKE
310 320 330 340 350
CCDKPLLEKS HCIAEVEKDA IPENLPPLTA DFAEDKDVCK NYQEAKDAFL
360 370 380 390 400
GSFLYEYSRR HPEYAVSVLL RLAKEYEATL EECCAKDDPH ACYSTVFDKL
410 420 430 440 450
KHLVDEPQNL IKQNCDQFEK LGEYGFQNAL IVRYTRKVPQ VSTPTLVEVS
460 470 480 490 500
RSLGKVGTRC CTKPESERMP CTEDYLSLIL NRLCVLHEKT PVSEKVTKCC
510 520 530 540 550
TESLVNRRPC FSALTPDETY VPKAFDEKLF TFHADICTLP DTEKQIKKQT
560 570 580 590 600
ALVELLKHKP KATEEQLKTV MENFVAFVDK CCAADDKEAC FAVEGPKLVV

STQTALA

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