Anti-BACE1 / BACE Antibody (aa137-152) MX-C2954
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen | BACE1 / BACE antibody was raised against synthetic peptide from human BACE1. Percent identity by BLAST analysis: Human (100%). |
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conjugations | Unconjugated |
epitope | aa137-152 |
furification | Protein G purified |
host | Rabbit |
antibody | Anti-BACE1 / BACE Antibody (aa137-152) MX-C2954 |
modifications | Unmodified |
reactivity | Human |
ncbi | P56817 |
synonyms | NM_012104 NP_036236.1 |
restrictions | For research use only. |
specificity | KLH conjugated synthetic peptide comprising amino acids 137 - 152 [WEGELGTDLLCGAGFP] of the human beta-site APP-cleaving enzyme 1 isoform D (BACE) protein. |
storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
type | Primary |
target | BACE1 / BACE |
predicted | aa137-152 |
format | Unconjugated |
clonality | Polyclonal |
approved | ELISA (1:1000) |
application | ELISA |