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Anti-BACE1 / BACE Antibody (aa170-428, FITC) MX-C419463

Anti-BACE1 / BACE Antibody (aa170-428, FITC) MX-C419463

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against recombinant bACE1 (Phe170-Thr428)
conjugations Fluorescein
epitope aa170-428
furification Affinity purified
host Rabbit
antibody Anti-BACE1 / BACE Antibody (aa170-428, FITC) MX-C419463
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Human BACE1 / BACE
storage Store at 4°C for frequent use; -20°C to -80°C for up to one year. Avoid freeze-thaw cycles.
type Primary
usage Applications and images are for the unconjugated form of this antibody. The conjugated antibody has not been tested. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
target BACE1 / BACE
predicted aa170-428
format FITC Conjugated
clonality IgG Polyclonal
application ICC, Western blot, ELISA

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