Anti-BACE1 / BACE Antibody (APC) MX-C512693
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen | BACE1 / BACE antibody was raised against full-length recombinant corresponding to aa22-502 from BACE1 (AAH65492) with GST tag. MW of the GST tag alone is 26kD. |
---|---|
conjugations | Allophycocyanin.Also available Unconjugated or conjugated with AP, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE. |
furification | Protein A purified |
host | Mouse |
antibody | Anti-BACE1 / BACE Antibody (APC) MX-C512693 |
modifications | Unmodified |
reactivity | Human, Rat |
ncbi | P56817 |
synonyms | NM_012104 NP_036236.1 |
restrictions | For research use only. |
storage | Store at 4°C. Do not freeze. |
type | Primary |
target | BACE1 / BACE |
format | APC Conjugated |
clonality | IgG1,k Monoclonal |
application | Western blot, ELISA (applications tested for the base form of this product only) |