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Anti-BACE1 / BACE Antibody (Biotin) MX-C520908

Anti-BACE1 / BACE Antibody (Biotin) MX-C520908

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against full-length recombinant corresponding to aa22-502 from BACE1 (AAH65492) with GST tag. MW of the GST tag alone is 26kD.
conjugations Biotin.Also available Unconjugated or conjugated with AP, APC, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
furification Protein A purified
host Mouse
antibody Anti-BACE1 / BACE Antibody (Biotin) MX-C520908
modifications Unmodified
reactivity Human, Rat
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
storage Store at -20°C.
type Primary
target BACE1 / BACE
format Biotin Conjugated
clonality IgG1,k Monoclonal
application Western blot, ELISA (applications tested for the base form of this product only)

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