Anti-BACE1 / BACE Antibody (clone 61-3E7) MX-C180189
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against c-terminal peptide conjugated to thyroglobulin. |
|---|---|
| conjugations | Unconjugated |
| furification | Protein A purified |
| host | Mouse |
| antibody | Anti-BACE1 / BACE Antibody (clone 61-3E7) MX-C180189 |
| modifications | Unmodified |
| reactivity | Human, Mouse, Rat, Primate |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| type | Primary |
| target | BACE1 / BACE |
| format | Unconjugated |
| clonality | IgG1 Monoclonal [61-3E7] |
| application | IHC, Western blot |