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Anti-BACE1 / BACE Antibody (MaxLight 405) MX-C562356

Anti-BACE1 / BACE Antibody (MaxLight 405) MX-C562356

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against synthetic phosphopeptide corresponding to amino acid residues surrounding Ser498 of human BACE (KLH).
conjugations ML405.Also available Unconjugated or conjugated with AP, APC, Biotin, HRP, FITC, PE, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750.
furification Immunoaffinity purified
host Rabbit
antibody Anti-BACE1 / BACE Antibody (MaxLight 405) MX-C562356
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
storage Store at -20°C.
type Primary
target BACE1 / BACE
format MaxLight 405 Conjugated
clonality IgG Polyclonal
application IHC, Western blot (applications tested for the base form of this product only)

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