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Anti-BACE1 / BACE Antibody MX-C3876

Anti-BACE1 / BACE Antibody MX-C3876

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against solubilized total recombinant protein.
conjugations Unconjugated.Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
furification Protein A/G purified
host Rabbit
antibody Anti-BACE1 / BACE Antibody MX-C3876
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Recognizes human BACE1. Cross-reactivity with BACE2 is almost negligible.
storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
type Primary
usage Suitable for use in Western Blot. Western Blot: 0.25-1.0 ug/ml. Positive control: SH-SY5Y neuroblastoma cell lysate.
target BACE1 / BACE
format Unconjugated
clonality IgG Polyclonal
application Western blot (applications tested for the base form of this product only)

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