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Anti-BACE1 / BACE Antibody MX-C3879

Anti-BACE1 / BACE Antibody MX-C3879

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against synthetic peptide from human BACE1.
conjugations Unconjugated
失败 1,000 µl Reconstitute in 1 ml of Sterile PBS.
furification Protein G purified
host Mouse
antibody Anti-BACE1 / BACE Antibody MX-C3879
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Recognizes human BACE-1. This antibody was selected for its ability to detect human or mouse BACE-1 in Western Blots and direct ELISAs. In Western Blots, no cross-reactivity was observed with rhBACE-2, rmBACE-2, rhADAM8, rmADAM9, rmADAM10, rhADAM15, or rh
storage Store at -20°C prior to reconstitution. After reconstitution aliquot and freeze at-20°C. Avoid frequent freeze thaws.
type Primary
usage Western Blot-This antibody can be used at 1-2 ug/mL with the appropriate secondary reagents to detect human or mouse BACE-1. Using a colorimetric detection system, the detection limit for rhBACE-1 is approximately 5 ng/lane under non-reducing and reducing
target BACE1 / BACE
format Unconjugated
clonality IgG Monoclonal
application Western blot, Flow Cytometry, ELISA

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