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Anti-BACE1 / BACE Antibody MX-C483693

Anti-BACE1 / BACE Antibody MX-C483693

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Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against recombinant Human BACE1 protein
conjugations Unconjugated
host Rabbit
antibody Anti-BACE1 / BACE Antibody MX-C483693
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Human BACE1 / ASP2 Has cross-reactivity in ELISA withMouse BACE1 / ASP2No cross-reactivity in ELISA withHuman ADAM15
storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
type Primary
target BACE1 / BACE
format Unconjugated
clonality Polyclonal
application Unconjugated

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