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Anti-BACE1 / BACE Antibody MX-C489920

Anti-BACE1 / BACE Antibody MX-C489920

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Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against recombinant Human BACE1 / ASP2 protein
conjugations Unconjugated
host Rabbit
antibody Anti-BACE1 / BACE Antibody MX-C489920
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Human BACE1 / ASP2Has cross-reactivity in ELISA withMouse BACE1Human ADAM15
storage Store at +4°C. Do not freeze. Protect from light.
type Primary
target BACE1 / BACE
format Unconjugated
clonality Polyclonal
application Unconjugated

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