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Anti-BACE1 / BACE Antibody (Ser498, AP) MX-C275348

Anti-BACE1 / BACE Antibody (Ser498, AP) MX-C275348

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against kLH-conjugated synthetic phosphopeptide from amino acids around Ser498 of human BACE.
conjugations Alkaline Phosphatase.Also available Unconjugated or conjugated with APC, Biotin, HRP, FITC, PE, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750.
epitope Ser498
furification Affinity purified
host Rabbit
antibody Anti-BACE1 / BACE Antibody (Ser498, AP) MX-C275348
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Human BACE1 / BACE
storage May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months.
type Primary
usage The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
target BACE1 / BACE
predicted Ser498
format AP Conjugated
clonality IgG Polyclonal
application IHC, Western blot, ELISA (applications tested for the base form of this product only)

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