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Anti-BACE2 Antibody (aa325-340) MX-C2956

Anti-BACE2 Antibody (aa325-340) MX-C2956

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen BACE2 antibody was raised against synthetic peptide from human BACE2. Percent identity by BLAST analysis: Human, Monkey (100%); Dog (93%).
conjugations Unconjugated
epitope aa325-340
furification Protein G purified
host Rabbit
antibody Anti-BACE2 Antibody (aa325-340) MX-C2956
modifications Unmodified
reactivity Human, Monkey
ncbi Q9Y5Z0
reconstitution Dog (at least 90% immunogen sequence identity)
synonyms NM_012105 NP_036237.2
restrictions For research use only.
specificity KLH conjugated synthetic peptide comprising amino acids 325 - 340 [RASLLYIQPMMGAGLC] of the human beta-site APP-cleaving enzyme 2 isoform C (BACE2) protein.
storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
type Primary
target BACE2
predicted aa325-340
format Unconjugated
clonality Polyclonal
approved ELISA (1:1000)
application ELISA

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