Anti-BACE2 Antibody (aa351-368) MX-C2953
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against synthetic peptide from human BACE2. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Bovine, Dog, Pig (83%). |
|---|---|
| conjugations | Unconjugated |
| epitope | aa351-368 |
| furification | Protein G purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (aa351-368) MX-C2953 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | KLH conjugated synthetic peptide comprising amino acids 351 - 368 [PWSYFPKIISIYLRDECA] of the human beta-site APP-cleaving enzyme 2 (BACE2) protein. |
| storage | Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles. |
| type | Primary |
| target | BACE2 |
| predicted | aa351-368 |
| format | Unconjugated |
| clonality | Polyclonal |
| approved | ELISA (1:1000) |
| application | ELISA |