Anti-BACE2 Antibody (aa496-511) MX-C3885
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against a peptide corresponding to amino acids 496 to 511 of human BACE2 (4). |
|---|---|
| conjugations | Unconjugated |
| epitope | aa496-511 |
| furification | Immunoaffinity purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (aa496-511) MX-C3885 |
| modifications | Unmodified |
| reactivity | Human, Mouse, Rat |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | Recognizes human BACE2. Species cross-reactivity: Mouse and rat. |
| storage | Long term: Add glycerol (40-50%) -20°C; Short term: +4°C |
| type | Primary |
| usage | Suitable for use in ELISA, Western Blot. Western Blot: 0.5-1 ug/ml. Positive control: Human heart tissue lysate can be used as positive control. |
| target | BACE2 |
| predicted | aa496-511 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | Western blot, ELISA |