Anti-BACE2 Antibody (C-Terminus) MX-C326903
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen | BACE2 antibody was raised against synthetic peptide selected from the C-terminal region of human BACE2C (KLH). |
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conjugations | Unconjugated.Also available conjugated with APC, AP, FITC, Biotin, HRP, PE, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750. |
epitope | C-Terminus |
furification | Affinity purified |
host | Rabbit |
antibody | Anti-BACE2 Antibody (C-Terminus) MX-C326903 |
modifications | Unmodified.Also available Azide-free. |
reactivity | Human |
ncbi | Q9Y5Z0 |
synonyms | NM_012105 NP_036237.2 |
restrictions | For research use only. |
specificity | Human BACE2 |
storage | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months |
type | Primary |
target | BACE2 |
predicted | C-Terminus |
format | Unconjugated |
clonality | IgG Polyclonal |
application | IHC, Western blot, ELISA (applications tested for the base form of this product only) |