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Anti-BACE2 Antibody (Internal) MX-C326902

Anti-BACE2 Antibody (Internal) MX-C326902

详情

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen BACE2 antibody was raised against synthetic peptide selected from the center region of human BACE2 (KLH).
conjugations Unconjugated.Also available conjugated with AP, APC, Biotin, FITC, HRP, PE, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750.
epitope Internal
furification Affinity purified
host Rabbit
antibody Anti-BACE2 Antibody (Internal) MX-C326902
modifications Unmodified.Also available Azide-free.
reactivity Human
ncbi Q9Y5Z0
synonyms NM_012105 NP_036237.2
restrictions For research use only.
specificity Human BACE2
storage May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.
type Primary
target BACE2
predicted Internal
format Unconjugated
clonality IgG Polyclonal
application Western blot, Flow Cytometry, ELISA (applications tested for the base form of this product only)

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