Anti-BACE2 Antibody MX-C483697
详情
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen | BACE2 antibody was raised against recombinant Mouse BACE2 / Beta secretase 2 protein |
---|---|
conjugations | Unconjugated |
host | Rabbit |
antibody | Anti-BACE2 Antibody MX-C483697 |
modifications | Unmodified |
reactivity | Mouse |
ncbi | Q9Y5Z0 |
synonyms | NM_012105 NP_036237.2 |
restrictions | For research use only. |
specificity | Mouse BACE2 / Beta secretase 2 |
storage | Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles. |
type | Primary |
target | BACE2 |
format | Unconjugated |
clonality | Polyclonal |
application | Unconjugated |