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Anti-BTK Antibody (Internal) MX-C413087

Anti-BTK Antibody (Internal) MX-C413087

详情

Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members.
immunogen BTK antibody was raised against kLH-conjugated synthetic peptide encompassing a sequence within the central region of human BTK.
conjugations Unconjugated
epitope Internal
furification Immunoaffinity purified
host Rabbit
antibody Anti-BTK Antibody (Internal) MX-C413087
modifications Unmodified
reactivity Human, Monkey, Mouse, Rat, Bovine
ncbi Q06187
synonyms NM_000061 NP_000052.1
restrictions For research use only.
specificity Recognizes endogenous levels of BTK protein.
storage Aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
type Primary
target BTK
predicted Internal
format Unconjugated
clonality Polyclonal
application IHC - Paraffin, Western blot

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