MC19209 Ninhydrin [485-47-2]
Details
Name | Ninhydrin |
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Synonyms | Trioxohydrindene monohydrate, 1,2,3-Indantrione monohydrate, 2,2-Dihydroxy-1,3-indanedione, Ninhydrin |
Empirical Formula (Hill Notation) | C9H6O4 |
CAS Number | 485-47-2 |
Molecular Weight | 178.14 |
MDL | MFCD00003791 |
Purity | AR,≥98%(HPLC) |
文档信息
文档 | COA NMR HPLC MSDS Datasheet |
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生物活性
描述 | Ninhydrin is a chromogenic analytical probe for amino acid and protein quantitative analysis |
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Related areas |
Research area >> Other Signal transduction >> Others >> Other |
Target | IC50: chromogenic analytical probe[1] |
In vitro | Ninhydrin (triketohydrindene hydrate) is used to assess amino acid qualitatively and quantitatively in ninhydrin reaction. All amino acids having α amino group, when heated in excess of ninhydrin give a purple coloured product. Only proline and hydroxyproline- amino acids molecules which contain a secondary amino group produce yellow condensation product. The colour intensity is proportional to the concentration of amino acid i.e. ammonia from the amino groups. |
Reference |
[1]. Omar MA, et al. Utility of ninhydrin reagent for spectrofluorimetric determination of heptaminol in human plasma.Luminescence. 2018 Sep;33(6):1107-1112. [2]. Anantharaman S, et al. Ninhydrin-sodium molybdate chromogenic analytical probe for the assay of amino acids and proteins.rSpectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:897-903. |
Physical and chemical properties
Density | 1.7±0.1 g/cm3 |
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Boiling point | 449.3±45.0 °C at 760 mmHg |
Melting point | 250 °C (dec.)(lit.) |
Empirical Formula | C9H6O4 |
Molecular Weight | 178.141 |
Flash point | 239.7±25.2 °C |
Accurate quality | 178.026611 |
PSA | 74.60000 |
LogP | 1.07 |
Appearance | White to pale yellow crystal powder |
Steam pressure | 0.0±1.2 mmHg at 25°C |
Refractive index | 1.737 |
Storage conditions | Refrigerated sealing, placed in ventilation and dry places to avoid contact with other oxides. |
Stability |
1.Use and store according to specifications, and will not be decomposed to avoid contact with oxide. 2.Light-sensitive. |
Water Solubility | 0.1-0.5 g/100 mL at 20 ºC。 |
LDLo - Lowest published lethal dose |
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LD50 - Lethal dose, 50 percent kill |
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Synonyms |
2,2-Dihydroxy-1H-indene-1,3(2H)-dione |