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MC19209 Ninhydrin [485-47-2]

MC19209  Ninhydrin  [485-47-2]

Details

Name Ninhydrin
Synonyms Trioxohydrindene monohydrate, 1,2,3-Indantrione monohydrate, 2,2-Dihydroxy-1,3-indanedione, Ninhydrin
Empirical Formula (Hill Notation) C9H6O4
CAS Number 485-47-2
Molecular Weight 178.14
MDL MFCD00003791
Purity AR,≥98%(HPLC)

文档信息

文档 COA NMR HPLC MSDS Datasheet

生物活性

描述 Ninhydrin is a chromogenic analytical probe for amino acid and protein quantitative analysis
Related areas

Research area >> Other

Signal transduction >> Others >> Other

Target IC50: chromogenic analytical probe[1]
In vitro Ninhydrin (triketohydrindene hydrate) is used to assess amino acid qualitatively and quantitatively in ninhydrin reaction. All amino acids having α amino group, when heated in excess of ninhydrin give a purple coloured product. Only proline and hydroxyproline- amino acids molecules which contain a secondary amino group produce yellow condensation product. The colour intensity is proportional to the concentration of amino acid i.e. ammonia from the amino groups.
Reference

[1]. Omar MA, et al. Utility of ninhydrin reagent for spectrofluorimetric determination of heptaminol in human plasma.Luminescence. 2018 Sep;33(6):1107-1112.

[2]. Anantharaman S, et al. Ninhydrin-sodium molybdate chromogenic analytical probe for the assay of amino acids and proteins.rSpectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:897-903.

Physical and chemical properties

Density 1.7±0.1 g/cm3
Boiling point 449.3±45.0 °C at 760 mmHg
Melting point 250 °C (dec.)(lit.)
Empirical Formula C9H6O4
Molecular Weight 178.141
Flash point 239.7±25.2 °C
Accurate quality 178.026611
PSA 74.60000
LogP 1.07
Appearance White to pale yellow crystal powder
Steam pressure 0.0±1.2 mmHg at 25°C
Refractive index 1.737
Storage conditions Refrigerated sealing, placed in ventilation and dry places to avoid contact with other oxides.
Stability

1.Use and store according to specifications, and will not be decomposed to avoid contact with oxide.

2.Light-sensitive.

Water Solubility 0.1-0.5 g/100 mL at 20 ºC。
LDLo - Lowest published lethal dose
[1] ROUTE OF EXPOSURE :Oral
[2] SPECIES OBSERVED :Rodent - rat
[3] DOSE/DURATION :250 mg/kg
[4] TOXIC EFFECTS :Details of toxic effects not reported other than lethal dose value
LD50 - Lethal dose, 50 percent kill
[1]ROUTE OF EXPOSURE :Intraperitoneal
[2]SPECIES OBSERVED :Rodent - mouse
[3]DOSE/DURATION :78 mg/kg
[4]TOXIC EFFECTS :Behavioral - somnolence (general depressed activity) Vascular - regional or general arteriolar or venous dilation Lungs, Thorax, or Respiration - dyspnea
Synonyms

2,2-Dihydroxy-1H-indene-1,3(2H)-dione
Triketohydrinden Hydrate
Ninhydrin
2,2-Dihydroxy-1,3-indanedione
Ninhydrin,spectrophotometric grade
MFCD00003791
Ninhydrin Spray
Ningidrin
indane-1,2,3-trione monohydrate
NyNhydriN
NinhydrinGr
1,2,3-Indanetrione monohydrate
Trioxohydrindene monohydrate
Ninhydrin,ozone friendly ready to use spray
1H-Indene-1,2,3-trione hydrate
Ninhydrin (contains Acetic Acid) Ethanol
1,2,3-Indantrione, 2-hydrate
EINECS 207-618-1
NINHYDRINE
1,2,3-triketohydrindene hydrate
1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-
2,2-dihydroxy-2H-indene-1,3-dione
Ninhydrin hydrate
NinhydrinA.R.
NIN
Ninthydrin
1,3-Indandione, 2,2-dihydroxy-
1,2,3-Indantrione monohydrate
1,2,3-Indantrione monohydrate,2,2-Dihydroxy-1,3-indanedione,Trioxohydrindene monohydrate

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