MC28388 ARGLABIN [84692-91-1]
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Details
| 英文名称 | arglabin |
|---|---|
| 别名 | 小白菊内酯衍生物;(3aR,4aS)-1,4aα-Dimethyl-7-methylene-4a,5,6,6aα,9aβ,9bα-hexahydro-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(7H)-one;(3aS)-2,3,3aβ,4,5β,6,6a,7,9aβ,9bα-Decahydro-6α,6aα-epoxy-6,9-dimethyl- |
| 分子式 | C15H18O3 |
| CAS号 | 84692-91-1 |
| 分子量 | 246.304 |
| MDL | NA |
| 名称 | ARGLABIN |
| 介绍 | 分析标准品,HPLC≥98% |
文档信息
| 文档 | COA NMR HPLC MSDS Datasheet |
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生物活性
| 描述 | Arglabin由亮绿蒿中提取获得的天然产物，具有抗癌活性。 |
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| 相关类别 |
研究领域 >> 癌症 信号通路 >> 免疫及炎症 >> NOD样受体(NLR) 天然产物 >> 萜类化合物和糖苷 |
| 参考文献 |
[1]. Bottex-Gauthier C, et al. In vitro biological activities of arglabin, a sesquiterpene lactone from the Chinese herb Artemisia myriantha Wall. (Asteraceae). Biotechnol Ther. 1993;4(1-2):77-98. [2]. Abil'daeva AZh, et al. Anti-inflammatory effect of arglabin and 11,13-dihydro-13-dimethylaminoarglabin hydrochloride. Eksp Klin Farmakol. 2004 Jan-Feb;67(1):37-9. [3]. Zhang Q, et al. Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells. J Med Chem. 2012 Oct 25;55(20):8757-69. |
物理化学性质
| 密度 | 1.2±0.1 g/cm3 |
|---|---|
| 沸点 | 404.6±45.0 °C at 760 mmHg |
| 分子式 | C15H18O3 |
| 分子量 | 246.302 |
| 闪点 | 171.3±23.3 °C |
| 精确质量 | 246.125595 |
| PSA | 38.83000 |
| LogP | 1.74 |
| 蒸汽压 | 0.0±0.9 mmHg at 25°C |
| 折射率 | 1.571 |
英文别名
| 别名 |
3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one, 5,6,6a,7,9a,9b-hexahydro-1,4a-dimethyl-7-methylene-, (3aR,4aS,6aS,9aS,9bR)- 3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one, 5,6,6a,7,9a,9b-hexahydro-1,4a-dimethyl-7-methylene-, (3aR,4aS,6aS,9aS,9bR)- (3aR,4aS,6aS,9aS,9bR)-1,4a-Dimethyl-7-methylene-5,6,6a,7,9a,9b-hexahydro-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one (+)-Arglabin |
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