MC61052 Arbidol Hydrochloride Hydrate 盐酸阿比朵尔水合物 [131707-23-8]
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Details
| 英文名称 | NA |
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| 别名 | NA |
| 分子式 | C22H28BrClN2O4S |
| CAS号 | 131707-23-8 |
| 分子量 | 531.89 |
| MDL | MFCD00344795 |
| 名称 | 盐酸阿比朵尔水合物 |
| 介绍 | 98% |
文档信息
| 文档 | COA NMR HPLC MSDS Datasheet |
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生物活性
| 描述 | Arbidol (Umifenovir)盐酸盐是广谱的抗病毒化合物，能通过阻断病毒与宿主细胞的融合抑制包装病毒进入细胞。 |
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| 相关类别 |
研究领域 >> 感染 信号通路 >>抗感染 >> 流感病毒 |
| 参考文献 |
[1]. Shi L, et al. Antiviral activity of arbidol against influenza A virus, respiratory syncytial virus, rhinovirus, coxsackie virus and adenovirus in vitro and in vivo. Arch Virol. 2007;152(8):1447-55. [2]. Teissier E, et al. Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol. PLoS One. 2011 Jan 25;6(1):e15874. [3]. Zhong Q, et al. Antiviral activity of Arbidol against Coxsackie virus B5 in vitro and in vivo. Arch Virol. 2009;154(4):601-7. |
物理化学性质
| 沸点 | 591.8ºC at 760 mmHg |
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| 熔点 | 133-137ºC |
| 分子式 | C22H26BrClN2O3S |
| 分子量 | 513.875 |
| 精确质量 | 512.053589 |
| PSA | 80.00000 |
| LogP | 5.97900 |
| 外观性状 | 白色或灰白色结晶粉末 |
| 蒸汽压 | 1.34E-14mmHg at 25°C |
| 储存条件 | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| 稳定性 | Hygroscopic |
英文别名
| 别名 |
1-methyl-2-phenylthiomethyl-3-carbethoxy-4-dimetylaminomethyl-5-hydroxy-6-bromoindole hydrogen chloride Arbidol Hydrochloride 6-Bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylic Acid Ethyl Ester Moonohydrochloride Ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylsulfanyl)methyl]-1H-indole-3-carboxylate hydrochloride (1:1) 1-methyl-2-phenylthiomethyl-3-carbethoxy-4-dimethylaminomethyl-5-oxy-6-bromindol hydrochloride Arbidol Hydrochloride Hydrate arbidol hydrogen chloride 1H-Indole-3-carboxylic acid, 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-, ethyl ester, hydrochloride (1:1) umifenovir hydrogen chloride Arbidol HCl MFCD00333871 umifenovir hydrochloride Arbidol (hydrochloride) |
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