Anti-BACE1 / BACE Antibody (aa170-428, Biotin) MX-C419464
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against recombinant bACE1 (Phe170-Thr428) |
|---|---|
| conjugations | Biotin |
| epitope | aa170-428 |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (aa170-428, Biotin) MX-C419464 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Human BACE1 / BACE |
| storage | Store at 4°C for frequent use; -20°C to -80°C for up to one year. Avoid freeze-thaw cycles. |
| type | Primary |
| usage | Applications and images are for the unconjugated form of this antibody. The conjugated antibody has not been tested. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| target | BACE1 / BACE |
| predicted | aa170-428 |
| format | Biotin Conjugated |
| clonality | IgG Polyclonal |
| application | ICC, Western blot, ELISA |