Anti-BACE1 / BACE Antibody (aa170-428) MX-C372590
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against recombinant bACE1 (Phe170-Thr428) |
|---|---|
| conjugations | Unconjugated |
| epitope | aa170-428 |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (aa170-428) MX-C372590 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Human BACE1 / BACE |
| storage | Store at 4°C for frequent use; -20°C to -80°C for up to one year. Avoid freeze-thaw cycles. |
| type | Primary |
| target | BACE1 / BACE |
| predicted | aa170-428 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | Western blot, ELISA |