Anti-BACE1 / BACE Antibody (aa181-366) MX-C292996
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against recombinant bACE1 (Gly181-Tyr366) expressed in E. coli. |
|---|---|
| conjugations | Unconjugated.Also available conjugated with Biotin, FITC. |
| epitope | aa181-366 |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (aa181-366) MX-C292996 |
| modifications | Unmodified |
| reactivity | Rat |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Rat BACE1 / BACE |
| storage | Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles. |
| type | Primary |
| target | BACE1 / BACE |
| predicted | aa181-366 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | Western blot, ELISA (applications tested for the base form of this product only) |