Anti-BACE1 / BACE Antibody (Asp492) MX-C176262
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against synthetic peptide around Asp492 of human BACE1 / BACE |
|---|---|
| conjugations | Unconjugated |
| epitope | Asp492 |
| furification | Immunoaffinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (Asp492) MX-C176262 |
| modifications | Unmodified |
| reactivity | Human, Mouse, Rat |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Human BACE1 / BACE |
| storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| type | Primary |
| target | BACE1 / BACE |
| predicted | Asp492 |
| format | Unconjugated |
| clonality | Polyclonal |
| application | IHC - Paraffin, Immunofluorescence |