Anti-BACE1 / BACE Antibody (Biotin) MX-C523516
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen | BACE1 / BACE antibody was raised against solubilized total recombinant protein. |
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conjugations | Biotin.Also available Unconjugated or conjugated with AP, APC, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE. |
furification | Protein A/G purified |
host | Rabbit |
antibody | Anti-BACE1 / BACE Antibody (Biotin) MX-C523516 |
modifications | Unmodified |
reactivity | Human |
ncbi | P56817 |
synonyms | NM_012104 NP_036236.1 |
restrictions | For research use only. |
storage | Store at 4°C. |
type | Primary |
target | BACE1 / BACE |
format | Biotin Conjugated |
clonality | IgG Polyclonal |
application | Western blot (applications tested for the base form of this product only) |