Anti-BACE1 / BACE Antibody (C-Terminus) MX-C188872
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against synthetic peptide corresponding to 17aa at the C-terminus of human BACE. |
|---|---|
| conjugations | Unconjugated |
| epitope | C-Terminus |
| furification | Purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (C-Terminus) MX-C188872 |
| modifications | Unmodified |
| reactivity | Human, Mouse |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Human BACE. Species Crossreactivity: mouse. |
| storage | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months. |
| type | Primary |
| target | BACE1 / BACE |
| predicted | C-Terminus |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | ICC, Western blot |