Anti-BACE1 / BACE Antibody (MaxLight 490) MX-C582008
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against synthetic phosphopeptide corresponding to amino acid residues surrounding Ser498 of human BACE (KLH). |
|---|---|
| conjugations | ML490.Also available Unconjugated or conjugated with AP, APC, Biotin, HRP, FITC, PE, MaxLight 405, MaxLight 550, MaxLight 650, MaxLight 750. |
| furification | Immunoaffinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (MaxLight 490) MX-C582008 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| storage | Store at -20°C. |
| type | Primary |
| target | BACE1 / BACE |
| format | MaxLight 490 Conjugated |
| clonality | IgG Polyclonal |
| application | IHC, Western blot (applications tested for the base form of this product only) |