Anti-BACE1 / BACE Antibody MX-C126949
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against recombinant corresponding to human BACE, EC Domain. |
|---|---|
| conjugations | Unconjugated |
| failed | 100 µl Sterile PBS |
| furification | Immunoaffinity purified |
| host | Mouse |
| antibody | Anti-BACE1 / BACE Antibody MX-C126949 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P56817 |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Recognizes human BACE, asp2. |
| storage | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. |
| type | Primary |
| usage | Suitable for use in ELISA, Flow Cytometry, and Western Blot. ELISA: 1:10000-100000; 50-100 ng control antigen/well. Western Blot: 1-5 ug/ml (chemiluminescence). Flow Cytometry: ~1 ug/10^6. |
| target | BACE1 / BACE |
| format | Unconjugated |
| clonality | IgG1 Monoclonal |
| application | Western blot, Flow Cytometry, ELISA |