Anti-BACE1 / BACE Antibody MX-C193929
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| immunogen | BACE1 / BACE antibody was raised against a synthetic peptide of part of human BACE1 (RLPRETDEEPEEPGRR). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Marmoset, Rat (100%); Mouse, Hamster, Panda, Cat, Bovine (94%); Dog, |
|---|---|
| conjugations | Unconjugated |
| failed | 1 ml Distilled water |
| furification | Immunoaffinity purified |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody MX-C193929 |
| modifications | Unmodified |
| reactivity | Human, Monkey, Rat |
| ncbi | P56817 |
| reconstitution | Mouse, Bovine, Hamster (at least 90% immunogen sequence identity) |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | Human BACE1 / BACE |
| storage | Prior to reconstitution, +4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles. |
| type | Primary |
| target | BACE1 / BACE |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | ICC, Western blot |