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Anti-BACE1 / BACE Antibody MX-C309576

Anti-BACE1 / BACE Antibody MX-C309576

Details

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen BACE1 / BACE antibody was raised against full length human BACE1, aa1-476 (NP_620428.1).
conjugations Unconjugated.Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
furification Affinity purified
host Rabbit
antibody Anti-BACE1 / BACE Antibody MX-C309576
modifications Unmodified
reactivity Human
ncbi P56817
synonyms NM_012104 NP_036236.1
restrictions For research use only.
specificity Human BACE1 / BACE
storage May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months.
type Primary
target BACE1 / BACE
format Unconjugated
clonality IgG Polyclonal
application Western blot (applications tested for the base form of this product only)

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