Anti-BACE1 / BACE Antibody MX-C309576
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
immunogen | BACE1 / BACE antibody was raised against full length human BACE1, aa1-476 (NP_620428.1). |
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conjugations | Unconjugated.Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE. |
furification | Affinity purified |
host | Rabbit |
antibody | Anti-BACE1 / BACE Antibody MX-C309576 |
modifications | Unmodified |
reactivity | Human |
ncbi | P56817 |
synonyms | NM_012104 NP_036236.1 |
restrictions | For research use only. |
specificity | Human BACE1 / BACE |
storage | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. |
type | Primary |
target | BACE1 / BACE |
format | Unconjugated |
clonality | IgG Polyclonal |
application | Western blot (applications tested for the base form of this product only) |