Anti-BACE1 / BACE Antibody (Ser498) MX-C96708
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
| conjugations | Unconjugated |
|---|---|
| epitope | Ser498 |
| furification | Ammonium sulfate precipitation |
| host | Rabbit |
| antibody | Anti-BACE1 / BACE Antibody (Ser498) MX-C96708 |
| modifications | Unmodified |
| reactivity | Human, Mouse |
| ncbi | P56817 |
| reconstitution | Rat, Cow (at least 90% immunogen sequence identity) |
| synonyms | NM_012104 NP_036236.1 |
| restrictions | For research use only. |
| specificity | This BACE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-501 amino acids from human BACE. |
| storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| type | Primary |
| target | BACE1 / BACE |
| predicted | Ser498 |
| format | Unconjugated |
| clonality | Polyclonal |
| approved | Western blot (1:1000) |
| application | Western blot |