Anti-BACE2 Antibody (aa230-396, Biotin) MX-C300850
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against recombinant bACE2 (Met230-Phe396) expressed in E. coli. |
|---|---|
| conjugations | Biotin.Also available Unconjugated or conjugated with FITC. |
| epitope | aa230-396 |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (aa230-396, Biotin) MX-C300850 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | Human BACE2 |
| storage | Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles. |
| type | Primary |
| usage | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| target | BACE2 |
| predicted | aa230-396 |
| format | Biotin Conjugated |
| clonality | IgG Polyclonal |
| application | Western blot, ELISA (applications tested for the base form of this product only) |