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Anti-BACE2 Antibody (aa496-511) MX-C3885

Anti-BACE2 Antibody (aa496-511) MX-C3885

Details

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen BACE2 antibody was raised against a peptide corresponding to amino acids 496 to 511 of human BACE2 (4).
conjugations Unconjugated
epitope aa496-511
furification Immunoaffinity purified
host Rabbit
antibody Anti-BACE2 Antibody (aa496-511) MX-C3885
modifications Unmodified
reactivity Human, Mouse, Rat
ncbi Q9Y5Z0
synonyms NM_012105 NP_036237.2
restrictions For research use only.
specificity Recognizes human BACE2. Species cross-reactivity: Mouse and rat.
storage Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
type Primary
usage Suitable for use in ELISA, Western Blot. Western Blot: 0.5-1 ug/ml. Positive control: Human heart tissue lysate can be used as positive control.
target BACE2
predicted aa496-511
format Unconjugated
clonality IgG Polyclonal
application Western blot, ELISA

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