Anti-BACE2 Antibody (aa496-511) MX-C3885
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
immunogen | BACE2 antibody was raised against a peptide corresponding to amino acids 496 to 511 of human BACE2 (4). |
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conjugations | Unconjugated |
epitope | aa496-511 |
furification | Immunoaffinity purified |
host | Rabbit |
antibody | Anti-BACE2 Antibody (aa496-511) MX-C3885 |
modifications | Unmodified |
reactivity | Human, Mouse, Rat |
ncbi | Q9Y5Z0 |
synonyms | NM_012105 NP_036237.2 |
restrictions | For research use only. |
specificity | Recognizes human BACE2. Species cross-reactivity: Mouse and rat. |
storage | Long term: Add glycerol (40-50%) -20°C; Short term: +4°C |
type | Primary |
usage | Suitable for use in ELISA, Western Blot. Western Blot: 0.5-1 ug/ml. Positive control: Human heart tissue lysate can be used as positive control. |
target | BACE2 |
predicted | aa496-511 |
format | Unconjugated |
clonality | IgG Polyclonal |
application | Western blot, ELISA |