Anti-BACE2 Antibody (C-Terminus, AP) MX-C224881
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against kLH-conjugated synthetic peptide from the C-terminus of human BACE2C. |
|---|---|
| conjugations | Alkaline Phosphatase.Also available Unconjugated or conjugated with APC, FITC, Biotin, HRP, PE, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750. |
| epitope | C-Terminus |
| furification | Protein G purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (C-Terminus, AP) MX-C224881 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | Human BACE2. |
| storage | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. |
| type | Primary |
| usage | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| target | BACE2 |
| predicted | C-Terminus |
| format | AP Conjugated |
| clonality | IgG Polyclonal |
| application | IHC, Western blot, ELISA (applications tested for the base form of this product only) |