Anti-BACE2 Antibody (C-Terminus) MX-C326903
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against synthetic peptide selected from the C-terminal region of human BACE2C (KLH). |
|---|---|
| conjugations | Unconjugated.Also available conjugated with APC, AP, FITC, Biotin, HRP, PE, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750. |
| epitope | C-Terminus |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (C-Terminus) MX-C326903 |
| modifications | Unmodified.Also available Azide-free. |
| reactivity | Human |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | Human BACE2 |
| storage | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months |
| type | Primary |
| target | BACE2 |
| predicted | C-Terminus |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | IHC, Western blot, ELISA (applications tested for the base form of this product only) |