Anti-BACE2 Antibody (MaxLight 490) MX-C582012
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against synthetic peptide corresponding to amino acids 44-59 of human BACE2 |
|---|---|
| conjugations | ML490.Also available conjugated with AP, Biotin, FITC, HRP, MaxLight 405, MaxLight 550, MaxLight 650, MaxLight 750, PE. |
| furification | Purified IgG |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody (MaxLight 490) MX-C582012 |
| modifications | Unmodified |
| reactivity | Human, Mouse, Rat |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| storage | Store at 4°C. |
| type | Primary |
| target | BACE2 |
| format | MaxLight 490 Conjugated |
| clonality | IgG Polyclonal |
| application | Western blot (applications tested for the base form of this product only) |