Anti-BACE2 Antibody MX-C501930
Details
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
| immunogen | BACE2 antibody was raised against recombinant Human Beta-secretase 2 protein (84-157AA) |
|---|---|
| conjugations | Unconjugated.Also available conjugated with FITC, Biotin, HRP. |
| furification | Protein G purified |
| host | Rabbit |
| antibody | Anti-BACE2 Antibody MX-C501930 |
| modifications | Unmodified |
| reactivity | Human, Rat |
| ncbi | Q9Y5Z0 |
| synonyms | NM_012105 NP_036237.2 |
| restrictions | For research use only. |
| specificity | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal f |
| storage | Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles. |
| type | Primary |
| target | BACE2 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | IHC, Immunofluorescence, Western blot, ELISA (applications tested for the base form of this product only) |