Anti-BCHE / Cholinesterase Antibody (aa151-200, FITC) MX-C446222
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | Synthetic peptide located between aa151-200 of human BCHE (P06276, NP_000046). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Shrew, Sheep, Elephant, Dog, Cat, Bovine, Bat, Horse, Opossum, Turkey, Chicken |
|---|---|
| conjugations | Fluorescein.Also available Unconjugated or conjugated with Biotin, HRP. |
| epitope | aa151-200 |
| furification | Protein A purified |
| host | Rabbit |
| antibody | Anti-BCHE / Cholinesterase Antibody (aa151-200, FITC) MX-C446222 |
| modifications | Unmodified |
| reactivity | Human, Chimpanzee, Orangutan, Gibbon, Mouse, Bat, Bovine, Dog, Horse, Sheep, Chicken |
| ncbi | P06276 |
| reconstitution | Monkey, Rat, Guinea pig, Pig, Rabbit (at least 90% immunogen sequence identity) |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Human BCHE |
| storage | Short term, +4°C. Long term, add glycerol to 40-50%, aliquot to avoid freeze/thaw cycles, and store at -20°C. Sensitive to light. |
| type | Primary |
| usage | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| target | BCHE / Cholinesterase |
| predicted | aa151-200 |
| format | FITC Conjugated |
| clonality | IgG Polyclonal |
| application | IHC - Paraffin, Western blot (applications tested for the base form of this product only) |