Anti-BCHE / Cholinesterase Antibody (aa151-200) MX-C40458
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | Synthetic peptide located between aa151-200 of human BCHE (P06276, NP_000046). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Mouse, Shrew, Sheep, Elephant, Dog, Cat, Bovine, Bat, Horse, Opossum, Turkey, Chicken |
|---|---|
| conjugations | Unconjugated.Also available conjugated with FITC, Biotin, HRP. |
| epitope | aa151-200 |
| failed | 100 µl After adding water, will consist of PBS buffer with 2% sucrose |
| furification | Protein A purified |
| host | Rabbit |
| antibody | Anti-BCHE / Cholinesterase Antibody (aa151-200) MX-C40458 |
| modifications | Unmodified |
| reactivity | Human, Mouse, Bat, Bovine, Dog, Horse, Sheep, Chicken |
| ncbi | P06276 |
| reconstitution | Monkey, Rat, Guinea pig, Pig, Rabbit (at least 90% immunogen sequence identity) |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Human BCHE |
| storage | Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles. |
| type | Primary |
| target | BCHE / Cholinesterase |
| predicted | aa151-200 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | IHC - Paraffin, Western blot (applications tested for the base form of this product only) |