Anti-BCHE / Cholinesterase Antibody (aa263-571) MX-C407739
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | E. coli-derived mouse BCHE recombinant protein (Position: K263-E571). Mouse BCHE shares 78% amino acid (aa) sequence identity with human BCHE. Percent identity by BLAST analysis: Human (100%); Rabbit, Horse (90%); Rat, Ferret, Sheep, Bovine, Guinea pig, A |
|---|---|
| conjugations | Unconjugated |
| epitope | aa263-571 |
| failed | Reconstitute with 200 µl of distilled water. |
| furification | Immunoaffinity purified |
| host | Rabbit |
| antibody | Anti-BCHE / Cholinesterase Antibody (aa263-571) MX-C407739 |
| modifications | Unmodified |
| reactivity | Mouse, Human |
| ncbi | P06276 |
| reconstitution | Horse, Rabbit (at least 90% immunogen sequence identity) |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Reacts with: mouse BCHE / Cholinesterase. |
| storage | Store lyophilized at -20°C. The reconstituted product can be stored for short term at 4 °C or long term at -20 °C or below. Avoid freeze/thaw cycles. |
| type | Primary |
| target | BCHE / Cholinesterase |
| predicted | aa263-571 |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| approved | Western blot (0.1 - 0.5 µg/ml) |
| application | Western blot |