Anti-BCHE / Cholinesterase Antibody (aa29-150, FITC) MX-C301924
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | Recombinant Human BCHE (Glu29-Thr150) expressed in E. coli. |
|---|---|
| conjugations | Fluorescein.Also available Unconjugated or conjugated with Biotin. |
| epitope | aa29-150 |
| furification | Affinity purified |
| host | Rabbit |
| antibody | Anti-BCHE / Cholinesterase Antibody (aa29-150, FITC) MX-C301924 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P06276 |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Human BCHE / Cholinesterase |
| storage | Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles. |
| type | Primary |
| usage | The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. |
| target | BCHE / Cholinesterase |
| predicted | aa29-150 |
| format | FITC Conjugated |
| clonality | IgG Polyclonal |
| application | Western blot, ELISA (applications tested for the base form of this product only) |