Anti-BCHE / Cholinesterase Antibody (clone 3E8) MX-C413904
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | Butyrylcholinesterase isolated from human plasma. |
|---|---|
| conjugations | Unconjugated |
| furification | Protein A/G purified |
| host | Mouse |
| antibody | Anti-BCHE / Cholinesterase Antibody (clone 3E8) MX-C413904 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P06276 |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| storage | Store at 4°C |
| type | Primary |
| usage | This antibody reacts with BtChE from normal serum when tested in sandwich ELISA using a polyclonal antibody against BtChE as capture antibody, and in crossed immunoelectrophoresis followed by incubation of the gel with It. Serum ChE activity has been meas |
| target | BCHE / Cholinesterase |
| format | Unconjugated |
| clonality | IgG1,k Monoclonal [3E8] |
| approved | ELISA (1:8000) |
| application | ELISA |