Anti-BCHE / Cholinesterase Antibody (clone 4C12) MX-C172572
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | Full length human recombinant protein of human BCHE (NP_000046) produced in HEK293T cell. |
|---|---|
| conjugations | Unconjugated |
| furification | Protein A/G purified |
| host | Mouse |
| antibody | Anti-BCHE / Cholinesterase Antibody (clone 4C12) MX-C172572 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P06276 |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Human BCHE / Cholinesterase |
| storage | Store at -20°C. Minimize freezing and thawing. |
| type | Primary |
| target | BCHE / Cholinesterase |
| format | Unconjugated |
| clonality | IgG1 Monoclonal [4C12] |
| approved | Western blot (1:2000) |
| application | Western blot |