Anti-BCHE / Cholinesterase Antibody MX-C347613
Details
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
| immunogen | This BCHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the Central region of human BCHE. |
|---|---|
| conjugations | Unconjugated |
| furification | Ammonium sulfate precipitation |
| host | Rabbit |
| antibody | Anti-BCHE / Cholinesterase Antibody MX-C347613 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | P06276 |
| synonyms | NM_000055 NP_000046.1 |
| restrictions | For research use only. |
| specificity | Human BCHE / Cholinesterase |
| storage | Long term: -20°C; Short term: -20°C |
| type | Primary |
| target | BCHE / Cholinesterase |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| approved | Western blot (1:1000) |
| application | Western blot |