Anti-BTK Antibody IHC-plus™ MX-B14229
Details
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members.
| immunogen | BTK antibody was raised against recombinant protein. |
|---|---|
| conjugations | Unconjugated |
| furification | Purified |
| host | Mouse |
| antibody | Anti-BTK Antibody IHC-plus™ MX-B14229 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | Q06187 |
| synonyms | NM_000061 NP_000052.1 |
| restrictions | For research use only. |
| specificity | Human BTK |
| storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| type | Primary |
| target | BTK |
| format | Unconjugated |
| clonality | Monoclonal |
| application | IHC - Paraffin, Western blot, Immunoprecipitation |