Anti-BTK Antibody MX-C659646
Details
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members.
| conjugations | Unconjugated |
|---|---|
| furification | Immunogen affinity purified |
| host | Rabbit |
| antibody | Anti-BTK Antibody MX-C659646 |
| modifications | Unmodified |
| reactivity | Human |
| ncbi | Q06187 |
| synonyms | NM_000061 NP_000052.1 |
| restrictions | For research use only. |
| storage | -20°C |
| type | Primary |
| target | BTK |
| format | Unconjugated |
| clonality | IgG Polyclonal |
| application | Unconjugated |